Pharmaceutical Organic Chemistry II Unit 1 Notes
Benzeneand its derivatives
A. Analytical, synthetic and other evidences in the derivation of structure
of benzene, Orbital picture, resonance in benzene, aromatic
characters, Huckel’s rule
B. Reactions of benzene- nitration, sulphonation, halogenation
reactivity, Friedelcrafts alkylation reactivity, limitations, Friedelcrafts acylation.
C. Substituents, effect of substituents on reactivity and orientation of
mono substituted benzene compounds towards electrophilic
substitution reaction
D. Structure and uses of DDT, Saccharin, BHC and Chloramine
Pharmaceutical Organic Chemistry – II All Unit Notes
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